# Demographics (birthdate)= ## Birthdate This data element is meant to define patient date of birth. The module describes the one of the common data elements group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The full date on which the patient was born, recorded in ISO 8601 formatted date.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#birthdate). (birthyear)= ## Birthyear **Data visualization** The four-digit year representing the patient’s year of birth. Used when full birthdate is unavailable due to privacy concerns or data minimization policies.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#birthyear). (birthplace)= ## Birthplace The country in which the patient was born. **Data visualization**

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#country-at-birth). (deathdate)= ## Deathdate This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The full date on which the patient's death, recorded in ISO 8601 formatted date. Also the underlying medical condition that directly led to the patient’s death.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#deathdate). (sex)= ## Sex This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The biological sex of the patient.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#sex). # Participation and timeline (first_visit)= ## First confirmed visit This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The date of the patient's first verified interaction with the healthcare system or enrollment in a study.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#first-confirmed-visit). (status)= ## Participation status This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** Indicates the current engagement of the patient in a healthcare program, study, or registry.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#participation-status). (symptoms_onset)= ## Symptoms onset This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The date (recorded in ISO 8601 formatted date) when the patient first noticed or reported symptoms related to the condition of interest, also described.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#symptoms-onset). # Conditions and findings (phenotype)= ## Phenotype This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** Describes qualitative observable characteristics, signs, or traits expressed by the patient.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#phenotype). (diagnosis)= ## Diagnosis This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** A clinically established identification of a disease or condition affecting the patient.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#diagnosis). # Clinical and molecular measurements (examination)= ## Examination **Data visualization** Clinical findings obtained from structured evaluations such as quantitative physical exams, body measurements or medical imaging.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#examination). (laboratory)= ## Laboratory **Data visualization** Quantitative or qualitative results from laboratory tests. Results can be represented including the measured value, units, anatomic structure and sample.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#laboratory). (genotype)= ## Genetic This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** Results from genomic analyses performed on the patient’s DNA or RNA. Findings may include details such as the specific genetic method, as well as the identified variants, the source of the biological sample, and zygosity information.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#genetic). # Patient-reported outcomes (questionnaire)= ## Questionnaire **Data visualization** Structured responses provided by the patient through standardized forms or surveys and standarized by Patient Reported Outcomes (PRO) or similar assessment questions.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#questionnaire). ## Disability This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** Measures the extent of impairment in the patient's physical, mental, or social functioning due to their health condition, captured using standardized scales or scores (e.g. WHODAS for general functioning).

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#disability). # Treatments and interventions (medication)= ## Medication Records of medications that have been prescribed or administered to the patient by a healthcare professional. Includes details such as drug name, dosage, frequency, route of administration, and medication duration. **Data visualization** The module shows how the individual, defined as a patient, participates in a drug administration procedure. At this process, the agent of this medication is defined, being the drug prescribed and its route of administration. Also this procedure has as output the medication as a prescription and its value, measured among its unit of measurement and frequency.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#medication). (Hospitalization)= ## Hospitalization **Data visualization** Records of inpatient stays, including dates of admission and discharge and the reason for hospitalization.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#hospitalization). (surgery)= ## Surgical intervention **Data visualization** Documentation of surgical procedures performed on the patient. Includes the type of surgery, date and description of the anatomical site.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#surgery). # Research (biobank)= ## Biobank This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** A record indicating whether the patient has donated biological samples for long-term storage in a biobank. This entry includes information on the type of samples collected, the date of collection, the sample accession number, and details about the biobank.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#biobank). (consent)= ## Consent This module describes the data element in the Common Data Elemments group. These elements, defined by the JRC, can be found on the EU RD Platform at [this link](https://eu-rd-platform.jrc.ec.europa.eu/sites/default/files/CDS/EU_RD_Platform_CDS_Final.pdf). **Data visualization** The module shows how the individual, defined as a patient, participates in an informed consent process that has as output the permission to be contacted or reusing his/her data. This output refers to the consent given by the individual.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#consent). (clinical_trial)= ## Clinical trial **Data visualization** Information about the patient’s enrollment in a clinical trials, including the associated diasease and condition and participant healthcare institute.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#clinical-trial). (cohort)= ## Cohort **Data visualization** Information about the patient’s enrollment in a cohort, including the associated diasease and condition and participant healthcare institute.

**RDF-Quad Examples:** Sample RDF-Quad representations of this data element are available, generated by our implementation workflows. [CARE-SM Implementation Github repository](https://github.com/CARE-SM/CARE-SM-Implementation/tree/main/RDF) **How to populate this data using CARE-SM:** A CSV glossary for this data element is described in our Implementation Guide. [Check our CSV Glossary](https://care-sm.readthedocs.io/en/latest/glossary.html#clinical-trial). # List of ontogies used | Prefix | Ontology Name or Namespace | Prefix IRI | |--------|--------------------------------------------------------|--------------------------------------------------| | obi | Ontology for Biomedical Investigations | http://purl.obolibrary.org/obo/OBI_ | | ncit | NCI Thesaurus | http://purl.obolibrary.org/obo/NCIT_ | | geno | Genotype Ontology | http://purl.obolibrary.org/obo/GENO_ | | sio | Semanticscience Integrated Ontology | http://semanticscience.org/resource/SIO_ | | obib | Ontology for Biobanking | http://purl.obolibrary.org/obo/OBIB_ | | duo | Data Use Ontology | http://purl.obolibrary.org/obo/DUO_ | | uo | Units of Measurement Ontology | http://purl.obolibrary.org/obo/UO_ | | maxo | Medical Action Ontology | http://purl.obolibrary.org/obo/MAXO_ | | opmi | Ontology of Precision Medicine and Investigation | http://purl.obolibrary.org/obo/OPMI_ | | ogms | Ontology for General Medical Science | http://purl.obolibrary.org/obo/OGMS_ | | iao | Information Artifact Ontology | http://purl.obolibrary.org/obo/IAO_ | | omit | Ontology for MIRNA Target | http://purl.obolibrary.org/obo/OMIT_ |